Efektifitas Antihiperglikemik Ekstrak Daun Salvia (Salvia occidentalis Sw.) Terhadap Mencit (Mus musculus)

نویسندگان

چکیده

Daun salvia (Salvia occidentalis Sw.) merupakan salah satu obat tradisional untuk menyembuhkan penyakit secara turun-temurun, yang diyakini memiliki khasiat DM (diabetes melitus). Diketahui mengandung senyawa kimia berupa alkaloid, flavonoid, tannin, polifenol dan saponin. Penelitian ini bertujuan mengetahui efektifitas ekstrak daun sebagai Antihiperglikemik terhadap Mencit (Mus muculus). diekstraksi dengan mengunakan metode maserasi, diuapkan menggunakan rotavapor. Analisis statistik dilakukan Statistica Produce and Service Solution (SPSS) ANOVA. Hasil analisis menunjukkan data berdistribusi normal homogen nilai normalitas 0,843 (p 0,05) homogenitas 0,526 (p≥0,05). Sehingga uji parametik signifikan 0,000(p≤0,05) sehingga terbukti dapat menurunkan kadar gulukosa darah pada mencit diinduksi aloksan konsentrasi 5%,10% 15% didapatkan paling optimal dalam penurunan glukosa dara muculus) adalah 5%.Salvia leaf ( Salvia is one of the traditional medicines for curing diseases from generation to generation, which believed have efficacy cure diabetes mellitus (DM). It known contain chemical compounds in form alkaloids, flavonoids, tannins, polyphenols saponins. This study aims determine effectiveness extract as an antihyperglycemic against mice Mus muculus ). The leaves were extracted using maceration method, evaporated a rotary evaporator. Statistical analysis was performed ANOVA . results showed that normally distributed homogeneous with normality value 0.843 0.05 ) homogeneity 0.526 (p≥0.05). So it carried out parametric test significant 0.000 (p≤0.05) so proven reduce blood glucose levels alloxan-induced at concentrations 5%, 10% most obtained decrease concentration 5%.

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ژورنال

عنوان ژورنال: Journal of Experimental and Clinical Pharmacy

سال: 2022

ISSN: ['2775-1368']

DOI: https://doi.org/10.52365/jecp.v2i2.429